T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on ...

The current path to CAR-T cell therapy is, by any measure, a logistical ordeal. A patient’s immune cells must be drawn out of ...

This article explores how advanced immune imaging technologies enable real-time visualization of immune responses, improving understanding of inflammation, autoimmunity, cancer therapy outcomes, and ...

A new form of CAR T kills leukemia, multiple myeloma, and sarcoma in mice, opening the door to a future off-the-shelf cancer ...

A breakthrough in CAR-T therapy may allow cancer treatment with a single injection, cutting costs and making care more available.

Scientists have found a way to make one of the most aggressive brain tumors vulnerable to the immune system. A single injection of a modified virus can invade glioblastoma, kill cancer cells, and ...

Scientists have developed a method to reprogram cancer-fighting immune cells directly inside the body, potentially eliminating the need for complex lab-based manufacturing. Early results show rapid ...

A study published in the journal Nature showed that the thymus, a small organ in the chest known for training the immune system in childhood, is also important for long-term health and lifespan.

Borrowing a cancer cell’s disguise, scientists shielded insulin-producing cells from attack by the immune system, a breakthrough that could pave the way for targeted type 1 diabetes treatments without ...

A tumor “don’t‑eat‑me” shield also hides pro‑immune danger signals; new antibodies that unmask this hidden cue could make cancers more vulnerable to immune attack.

Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

The immune system in the uterus can regenerate after both uterus transplantation and bone marrow transplantation. This is ...