Cells that acquire a doubled genome after a failed division step survive and proliferate far more effectively than cells left ...

Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many ...

Eukaryotic cells grow and divide through a specific series of cellular events. These events are tightly controlled, ensuring that the resultant daughter cells are free of DNA errors, and subject to ...

Yeast’s emergence as a model organism reshaped scientific discovery in cell biology, genetics, and more.

Biologists have uncovered a quality control timing mechanism tied to cell division. The 'stopwatch' function keeps track of mitosis and acts as a protective measure when the process takes too long, ...

A centromere is a specialized location in the DNA that functions as the control center of cell division and is maintained, unchanged, across generations of cells. It is characterized by a special ...

A cell copies all of its DNA, gears up to split in two, and then just… doesn’t. It sits there, swollen with a double genome, and nobody notices. This kind of silent failure has been observed in labs ...

“We closed a gap in our knowledge that was open for 10 years,” says Duccio Conti, a postdoc in the Musacchio group and first author of the publication. In healthy DNA replication, at first, each new ...