The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

A promising drug combination could help people with leukemia who don't respond to traditional treatments, according to new research. A team at Oregon Health and Science University made the discovery ...

Scientists could reshape cancer treatment by helping powerful drugs work better in the body by exploiting a surface protein called CD36 that helps pull substances into cells. This dramatically ...

A breast cancer drug paired with venetoclax significantly enhanced leukemia cell killing and durability in preclinical tests.

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body. Scientists at Duke University School of Medicine, University of Texas ...

A research team at Oregon Health & Science University (OHSU) has discovered a promising new drug combination that may help people with acute myeloid leukaemia overcome resistance to one of the most ...

Figure 6. Senescent heterogeneity model based on DNA content. Compared to G1-arrested cells, G2-arrested senescent cells express higher levels of senescence-associated markers, secrete more IL-6, and ...

In a recent study published in the journal Marine Drugs, researchers in Spain reviewed the bioactive potential of nudibranch-derived compounds, with emphasis on their antitumor properties. Cancer is ...

Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...