Mechanisms of heart-valve disease often mimic processes observed in embryonic and early childhood development, including activation of valvular interstitial cell (VIC) phenotypes and remodeling of ...

Background Patients with severe aortic stenosis (AS) are at high risk of mortality, regardless of symptom status. Despite ...

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification. They also theorize that other risk factors for CAVD, such as high ...

Researchers from the University of Basel in Switzerland have identified a key regulator gene for the formation of cardiac valves - a process crucial to normal embryonic heart development. These ...

Using a combination for spatial, single-cell transcriptomics and imaging data from 36 hearts, scientists from the KTH Royal Institute of Technology and their collaborators have come up with what they ...

UM cardiovascular experts lead pioneering stem cell research, developed a nationally recognized AHA certified model for ...

Fraunhofer IOF, startup NovaPump, and Jena University Hospital’s “pump cage” is cut out of a thin metal tube by laser. On the occasion of World Heart Day on September 29, the team reviewed the history ...

It’s a serious heart defect that can cause blood to flow into the wrong part of the heart chamber, and up until recently, it ...