Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing ...

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation. Retrotransposons ...

The first study on deuterium-depleted water (DDW) concluded that a higher D/H ratio inside cells can trigger cell division. This was supported by lab experiments showing that lowering deuterium levels ...

A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular mutation that impairs a crucial enzyme's ability to help drive energy ...

A newly published review article brings attention to the expanding role of RBM15, a critical regulator of RNA m6A methylation, in the development and progression of a wide range of diseases, including ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Outcomes of young-onset colorectal cancer vs late-onset colorectal cancer patients on phase 1 matched and non-matched therapies. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

Neutrophils are known as first responders to threatening infections and feature prominently in the microenvironment of tumors to resist cancer progression. Though neutrophils have been linked to the ...

If the genome is the blueprint of life, epigenetics is the control system that determines when, where, and how genes are expressed. By revealing how chemical modifications to DNA and chromatin shape ...

Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA ...