Obtaining frozen sections of bone tissue for intraoperative examination is challenging. To identify the bony edge of resection, orthopaedic oncologists therefore rely on pre-operative X-ray computed ...

Intravital two-photon microscopy enables deep-tissue imaging at high temporospatial resolution in live animals. However, the endosteal bone compartment and underlying bone marrow pose unique ...

A microscope picture of human bone cells (U2OS) showing the localization of a lipid (phosphatidylethanolamine). The lipid is visible in orange, the cell membrane in purple, and endosomes in white.

A biopsy is the only test that can confirm a cancer diagnosis. However, before doctors conduct a biopsy, they may take a person’s medical history, perform a physical exam, and order various imaging ...