Biologic therapy in HS shows dual benefits: improved skin lesions and potential systemic anti-inflammatory effects, as indicated by lipid profile changes. Early treatment initiation is crucial for ...

The US Food and Drug Administration (FDA) on Tuesday released new draft guidance clarifying how it plans to determine cases when real-world data may be sufficient for use in premarket and postmarket ...

Real world data is transforming clinical research, augmenting existing randomized controlled trial data to reduce risks and improve generalizability. With regulators setting clearer standards for ...

The European Medicines Agency (EMA) uses Data Analysis and Real-World Interrogation Network (DARWIN EU), a data network that became fully operational in 2024, to generate real-world evidence on ...

The majority of patients with early-stage disease Alzheimer’s disease (AD) had stable or improved cognition over roughly 1 year of treatment with lecanemab (Leqembi), a real-world analysis showed. The ...

In the late 1800s, the U.S. railroad system didn’t just revolutionize transportation—it catalyzed entirely new industries. Refrigerated railcars enabled a national meatpacking economy. Standard time ...

Blood-based multi-cancer early detection (MCED) has the potential to simultaneously screen for multiple deadly cancers with high positive predictive value. To assess real-world performance, we ...

Randomized clinical trials for people with non-small cell lung cancer (NSCLC) often fail to capture some of the nuances of the condition that significantly impact the quality of life for people with ...

Despite the medical advances of the modern age, more than 300 million people around the world still suffer from diseases for which there are no cures. Many cancers remain a death sentence. Alzheimer’s ...