AFM is a scanning probe microscopic instrument that consists of a force-sensing microcantilever, a laser source, a piezoelectric scanner and a photodiode detector (Figure 1A). During AFM imaging, the ...

Scientists at the Department of Energy's Oak Ridge National Laboratory have reimagined the capabilities of atomic force microscopy, or AFM, transforming it from a tool for imaging nanoscale features ...

New model extracts stiffness and fluidity from AFM data in minutes, enabling fast, accurate mechanical characterization of living cells at single-cell resolution. (Nanowerk Spotlight) Cells are not ...

Current optical and electron microscopy imaging techniques are not suited for measuring the dynamic characteristics of living microorganisms at tiny scales due to complex sample preparation methods or ...

Cryogenic optical microscopy uncovers multiple conformations of PIEZO1 in cell membranes, offering atomic-scale insights into how cells sense force. The team focused on PIEZO1, a mechanosensitive ion ...

Researchers have determined that condensates are electrically charged droplets that can induce voltage changes across the ...

Doing it yourself may not get you the most precise lab equipment in the world, but it gets you a hands-on appreciation of the techniques that just can’t be beat. Today’s example of this adage: [Stoppi ...

Escherichia coli bacteria imaged by high-speed inline force mapping and fluorescence microscopy. Simultaneous topography and elastic modulus maps show a stiffening of the division site. Light and ...