Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

As detailed in a Stanford-led study published in Nature, researchers successfully created a replica of a neuronal pathway responsible for pain transmission in a lab dish called an “assembloid.” The ...

Deep within the brain, scientists have uncovered a hidden “switch” that may decide whether pain fades away—or lingers for ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Subscribe to our newsletter for the ...

New research reveals that parts of the brain’s touch-processing center can actually strengthen with age, particularly the layer receiving incoming sensory signals. While deeper layers thin, they may ...

Researchers have discovered that a particular molecular signaling pathway plays an important role in producing osteoarthritis (OA) pain. Using a mouse model of painful osteoarthritis, they show that ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...