Gene transfer of SERCA2a improves contractility and myocardial energetics in the setting of heart failure Overexpression of SERCA2a has antiproliferative and vasodilatory effects on the vasculature ...
Acidification of intracellular compartments by the vacuolar-type H+-ATPases (VHA) is known to energize ion and metabolite transport, though cellular processes influenced by this activity are poorly ...
The rap sheet for β-CTF is growing longer. The C-terminal fragment, produced when β-secretase cleaves APP, binds to—and blocks assembly of—vacuolar ATPase, a proton pump that fuels acidification of ...
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